# Google Deepmind shifts genomics AI from bulk tissue predictions to single cell type resolution with AlphaGenome 2

Source: [The Decoder](https://the-decoder.com/google-deepmind-shifts-genomics-ai-from-bulk-tissue-predictions-to-single-cell-type-resolution-with-alphagenome-2/) · 2026-11-12 · AI
Page: https://themorning.dev/story/google-deepmind-shifts-genomics-ai-from-bulk-tissue-predictions-to-single-cell-t-4a2374108065ad81
Kind: release · Impact: medium

## In brief

- Google DeepMind has unveiled AlphaGenome 2, a genomics AI model.
- The model predicts effects of genetic variants for individual cell types instead of bulk tissue.
- It was trained on more than 107 million cell profiles and reportedly identifies nearly twice as many disease-relevant gene changes as its predecessor.

## Why it matters

Cell-type-level variant predictions could give researchers finer-grained insight into how genetic changes affect disease than bulk tissue models allow.

## Versions

- AlphaGenome 2

## Timeline

- 2026-11-12: Google DeepMind unveils AlphaGenome 2 (reported by The Decoder)

## Coverage

- [Google Deepmind shifts genomics AI from bulk tissue predictions to single cell type resolution with AlphaGenome 2](https://the-decoder.com/google-deepmind-shifts-genomics-ai-from-bulk-tissue-predictions-to-single-cell-type-resolution-with-alphagenome-2/) — The Decoder, 2026-11-12

Tags: genomics, ai-models, single-cell, variant-effect-prediction, deepmind

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Dev – https://themorning.dev